freckles

I think they are talking about something different

In the wild, there is no healthcare. In the wild healthcare is 'Ow, I hurt my leg. I can't run. A lion eats me, and I'm dead.' Well, I'm not dead. I'm the lion. You're dead.

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Merantes

I think it's important to understand the process a little better. First of all, the frequency of adverse effects is very low. It's about 1 in 2000 for any adverse event in the general population (I think the calculated number is 1:1879). Risk of serious adverse effect was much smaller. At these levels, you are talking about a very small number of people effected (in the clinical trials). If you see 4 adverse effects out of 10,000 patients or if you see 12 side effects, it is tough to safe if this difference is real or chance. There are statistical methods for calculating confidence in these numbers and that is where the argument lies. People are thinking that heart risk is like 1 in 3 of 1 in 10. That is not true.

Finally, this charge was in a study looking at Alzheimer's patients. The FDA was asking them questions about cardiovascular risk. Difficult to read garner much from those results.

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